Organic metal halides
Medchemexpress LLC COB-187 | 1862177-86-3 | 95.0% | 302.41 | 50 MG
COB-187 is a potent, ATP-competitive, and selective inhibitor of GSK-3β. It inhibits GSK-3 through a reversible and Cysteine (Cys)-199-dependent mechanism. COB-187 inhibits LPS-induced cytokine production and SARS-CoV-2 spike protein-induced CXCL10 production.
- Potent, ATP-competitive, and selective inhibitor of GSK-3β.
- Inhibits GSK-3 through a reversible and Cysteine (Cys)-199-dependent mechanism.
- Inhibits LPS-induced cytokine production.
- Inhibits SARS-CoV-2 spike protein-induced CXCL10 production.
Medchemexpress LLC BAY-677 | 2117404-84-7 | 98.0% | 400.35 | 10 MG
BAY-677 serves as an inactive control for BAY-678. BAY-678 is an orally bioavailable, highly potent, selective, and cell-permeable inhibitor of human neutrophil elastase (HNE), demonstrating an IC50 of 20 nM. This compound has also been nominated as a chemical probe to the public via the Structural Genomics Consortium (SGC).
- Inactive control for BAY-678.
- BAY-678 is an orally bioavailable inhibitor.
- Highly potent and selective inhibitor of human neutrophil elastase.
- Cell-permeable.
- IC50 of 20 nM against HNE.
- Nominated as a chemical probe by SGC.
Medchemexpress LLC Saroglitazar magnesium | 1639792-20-3 | 98.85% | 901.42 | 100 MG
Saroglitazar magnesium is a novel peroxisome proliferator-activated receptor (PPAR) agonist with predominant PPARα and moderate PPARγ activity, having EC50 values of 0.65 pM and 3 nM in HepG2 cells. This product is intended for research use only.
- Exhibits predominant PPARα and moderate PPARγ activity.
- Effective in preclinical models, reducing serum triglycerides, free fatty acids, and glucose dose-dependently.
- Potential therapeutic agent for treating dyslipidemia and diabetes.
Sigma Aldrich Fine Chemicals Biosciences Sodium acetate anhydrous B250G
SODIUM Sodium acetate anhydrous B250G
Medchemexpress LLC Tarloxotinib bromide | 1636180-98-7 | 98.8% | 681.77 | 50 MG
Tarloxotinib bromide (TH-4000) is an irreversible EGFR/HER2 inhibitor. It functions as a hypoxia-activated irreversible EGFR-TKI, demonstrating greater activity than erlotinib and exhibiting the therapeutic index necessary to inhibit WT EGFR in vivo, as evidenced by its ability to regress WT EGFR NSCLC tumor models. This product is intended for research use only.
- Irreversible EGFR/HER2 inhibitor
- Hypoxia-activated EGFR-TKI
- Greater activity compared with erlotinib
- Capable of regressing WT EGFR NSCLC tumor models
Medchemexpress LLC Tarloxotinib bromide | 1636180-98-7 | 98.8% | 681.77 | 1 MG
Tarloxotinib bromide (TH-4000) is an irreversible EGFR/HER2 inhibitor and a hypoxia-activated irreversible EGFR-TKI. This product appears as a light yellow to yellow solid with a high purity of 98.75%.
- Irreversible EGFR/HER2 inhibitor
- Hypoxia-activated irreversible EGFR-TKI
- High purity
- Appears as a light yellow to yellow solid
- Soluble in DMSO
- Suitable for in vitro and in vivo studies
Medchemexpress LLC Atropine methyl bromide | 2870-71-5 | 99.8% | 384.31 | 25 MG
Atropine methyl bromide is a muscarinic receptor (mAChR) antagonist. It is a quaternary ammonium salt of atropine and acts as a mydriatic for pupil dilation during ophthalmic examinations. Due to its highly polar nature, it is used to relieve pyloric spasms in infants and penetrates the central nervous system less readily than atropine.
- Acts as a muscarinic receptor antagonist
- Used as a mydriatic for pupil dilation
- Relieves pyloric spasm in infants
- Less central nervous system penetration compared to atropine due to high polarity
Medchemexpress LLC 1-Hexadecanaminium, N-hexadecyl-N,N-dimethyl-, bromide (1:1) | 70755-47-4 | 99.7% | 574.86 | 25 G
Dicetyldimonium bromide is a biochemical reagent that can be used as a biological material or organic compound for life science related research. It is intended for research use only and not for sale to patients.
- High purity: 99.71%
- Molecular weight: 574.86
- Chemical formula: C34H72BrN
- CAS number: 70755-47-4
- Appearance: White to off-white solid
- Soluble in DMSO at 2 mg/mL
Medchemexpress LLC Dicetyldimonium bromide | 70755-47-4 | 99.7% | 574.86 | 5 G
Dicetyldimonium bromide (Synonyms: Dimethyldipalmitylammonium bromide) is a biochemical reagent that can be used as a biological material or organic compound for life science related research. It is for research use only and not sold to patients.
- For research use only
- Not sold to patients